AT Virology Lab
About Us
The AT Lab is a virology research lab and is part of Mahidol University's department of Microbiology, under the Faculty of Science. Our lab is headed by Assoc. Prof. Arunee Thitithanyanont and our research centers on viral pathogenesis and virus-host interactions. Our expertise, accompanied by our BSL3 facility, enables us to investigate pandemic-causing viruses that include HIV, Avian Influenza (H5N1), and SARS-CoV-2, particularly to improve our understanding of the mechanisms involved during viral infections, which allows the development of strategies that help combat them.
Behind Our Science
The founding of our lab is concurrent to the establishment of a BSL-3 lab in Mahidol University's Department of Microbiology. This was driven by our PI's mission to leverage basic research to address diseases caused by microbial pathogens that are otherwise challenging to study without a proper facility. Her experiences serve as the guiding principles for our work.
Listen to hear about the journey ->
RESEARCH
Our understanding of the complex nature of our relationship with viruses remain lacking. In response to the necessity for therapeutic strategies against pandemic-causing viruses, studies in our lab provide a better understanding of viral pathogenesis that lay the foundation for improved disease diagnosis, better mitigation strategies and drug and vaccine development. The mission of our lab is to develop virus infection models, serological assays and viral discovery platforms; and utilize them in a vast array of applications including drug testing, vaccine development and disease surveillance.
Latest News & Events
Publications
- Andrographolide attenuates SARS-CoV-2 infection via an up-regulation of glutamate-cysteine ligase catalytic subunit (GCLC).
- The impact of N-glycans on the immune response of plant-produced SARS-CoV-2 RBD-Fc proteins.
- Heterologous Ad26.COV2.S booster after primary BBIBP-CorV vaccination against SARS-CoV-2 infection: 1-year follow-up of a phase 1/2 open-label trial.
- Phase II prefusion non-stabilised Covid-19 mRNA vaccine randomised study.
- Neutralizing activity of anti-respiratory syncytial virus monoclonal antibody produced in Nicotiana benthamiana.
- Infection kinetics, syncytia formation, and inflammatory biomarkers as predictive indicators for the pathogenicity of SARS-CoV-2 Variants of Concern in Calu-3 cells